Preparation, Characterization and Antibacterial Adhesion Performance of the Biomimetic Surfaces via Zwitterionic Self-assembly†

doi:10.7503/cjcu20140160

Abstract

Abstract:

A sulfobetaine zwitterionic compound, N,N-dimethylamino ethyl carbamate propyl triethoxysilane sulfonate(SiNNS), was designed and synthesized and its composition and molecular structure were characterized by means of FTIR and ¹H NMR spectroscopy. Furthermore, the biomimetic surface imitating the chemical features of cellular outer membrane were constructed via the self-assembly of SiNNS molecules on the hydroxylated glass surface. The morphology structure, chemical composition and wettability of the prepared biomimetic surface were characterized by atomic force microscopy(AFM), X-ray photoelectron spectroscopy(XPS) and contact angle measurement. The antifogging and antibacterial adhesion performances of the biomimetic surface were investigated using an untreated glass surface as a control sample. The results indicate that the zwitterionic self-assembled biomimetic surface can possess superhydrophilicity with a water contact angle of 9.2° and underwater superoleophobicity with an oil contact angle of 175.6°. Compared to the corresponding control sample, the zwitterionic self-assembled biomimetic surface can exhibit an excellent antifogging property and an obvious antibacterial adhesion performance.

Key words: Betaine-zwitterion, Self-assembly, Biomimetic surface, Superhydrophilicity, Antibacterial adhesion

CLC Number:

O647.4

TrendMD:

WU Yalu, LI Guangji, LIU Yunhong, CHEN Dayang. Preparation, Characterization and Antibacterial Adhesion Performance of the Biomimetic Surfaces via Zwitterionic Self-assembly^†[J]. Chem. J. Chinese Universities, 2014, 35(7): 1484.

Figures/Tables 9

Scheme 1 Synthesis routes of zwitterionic compound SiNNS

Fig.1 FTIR(A) and 1H NMR(B) spectra of SiNNS

Fig.2 AFM images and section plots for the SiNNS modified glass surfaces formed by soaking into 50 mmol/L SiNNS solution for different time Soaking time/min: (A) 0; (B) 30; (C) 60; (D) 90; (E) 120.

Fig.3 Schematic diagram of the formation of self-assembled membrane of zwitterionic compound iNNS on a hydroxylated glass surface

Fig.4 XPS spectra of the glass surface treated with 50 mmol/L SiNNS solution for 3 h (A) Full XPS spectrum of the treated surface; (B) the N1s region of the treated surface; (C) the S2p region of the treated surface.

Fig.5 Measurements of water droplet contact angles on different surfaces and oil droplet contact angles on Glass-SiNNS in different environments (A) Water droplet on Glass-B; (B) water droplet on Glass-OH; (C) water droplet on Glass-SiNNS; (D) oil droplet on Glass-SiNNS in air; (E) oil droplet on Glass-SiNNS under water.

Fig.6 Comparision of antifogging performance of Glass-SiNNS surface(left) and Glass-B surface(right)

Fig.7 Adhesion results of S. aureus(A, B) and E. Coli(C, D) on Glass-B surface(A, C) and Glass-SiNNS surface(B, D) contacted with bacterium suspension and cultured for different time (A1—D1) 6 h; (A2—D2) 12 h; (A3—D3) 36 h.

Fig.8 Variation of viable bacterial concentration with the culture time for bacterium suspension contacting with Glass-SiNNS surface (A)S. aureus; (B) E. coli.

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