Sdudy and Application of Mitoxantrone Sensor Based on Molecular Imprinting

Chem. J. Chinese Universities

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Sdudy and Application of Mitoxantrone Sensor Based on Molecular Imprinting

WU Wu-Ai, YIN Zhi-Fen, WEI Jing-Rui, GUO Man-Dong*

Department of Chemistry, Shanxi Normal University, Linfen 041004, China

Received:2008-04-10 Revised:1900-01-01 Online:2008-07-10 Published:2008-07-10
Contact: GUO Man-Dong

Abstract

Abstract: Under the condition of weak acidity, a sensitive film was prepared through the electropolymerization of o-aminophenol on a glassy carbon electrode surface in the presence of mitoxantrone which was considered as the template. A mitoxantrone sensor based on molecular imprinting was obtained. The sensor exhibits a good selectivity and sensitivity to mitoxantrone. The determination limit of the mitoxantrone was 1.6×10^-7 mol/L, and a linear relationship between the peak current and the mitoxantrone concentration was found in the range from 3.3×10^-7 to 1.0×10^-5 mol/L and from 1.0×10^-5 to 5.0×10^-5 mol/L. Also, the configuration and characteristics of the film were investigated in detail.

Key words: Molecular imprinting, Mitoxantrone, Sensor

CLC Number:

O657

TrendMD:

WU Wu-Ai, YIN Zhi-Fen, WEI Jing-Rui, GUO Man-Dong*. Sdudy and Application of Mitoxantrone Sensor Based on Molecular Imprinting[J]. Chem. J. Chinese Universities, doi: .

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Sdudy and Application of Mitoxantrone Sensor Based on Molecular Imprinting

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