Chem. J. Chinese Universities ›› 2004, Vol. 25 ›› Issue (11): 2054.

• Articles • Previous Articles     Next Articles

Synthesis of 5-Fluoro-4-deoxy-β-L-uridine

DONG Chun-Hong1, QI Xiu-Xiang3, YU Xue-Jun3, CHANG Jun-Biao1,2   

  1. 1. Department of Chemistry, University of Science and Technology of China, Hefei 230026, China;
    2. Quality Testing Research Center of Henan Academy of Science, Zhengzhou 450002, China;
    3. Lanzhou Institute of Chemical Physics, Academia Sinica, Lanzhou 730000, China
  • Received:2003-08-18 Online:2004-11-24 Published:2004-11-24

Abstract: We now report the syntheis here in a full account of 5-fluoro-4-deoxy-β-L-uridine. The structures of compounds were identified by the MS, UV, IR, 1H NMR spectra and elemental analyses. It is of interest to sythesize the L-nucleosides in anticipation of promising antiviral agents.

Key words: L-Nucleosides, Synthesis, Virus, HIV

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