Chem. J. Chinese Universities ›› 2002, Vol. 23 ›› Issue (1): 53.

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Synthesis of 3-Aryl-6-(6-/8-substituted-4-chloroquinoline-3-yl)-s- triazolo-1,3,4-thiadiazoles

QIAO Ren-Zhong1, HUI Xin-Ping1, ZHANG Zi-Yi1, CHENG Dong-Liang1   

  1. 1. College of Chemistry and Chemical Engineering, National Laboratory of Applied Organic Chemistry, Department of Chemistry, Lanzhou University, Lanzhou 730000, China;
    2. Department of Chemistry, Lanzhou Medical College, Lanzhou 730000, China
  • Received:2000-10-18 Online:2002-01-24 Published:2002-01-24

Abstract: Condensation of 4-amino-3-aryl-5-mercap to-1,2,4-triazole with 6-/8-substiuted-4-chloro|quinoline-3 carboxylic acid in the presence of phosphorus oxychloride gave 16 novel 3-aryl-6-(6-/8-substituted-4-chloroquinoline-3-yl)-s-triazolo-1,3,4-thiadiazoles(3a_3p). Their structures were determined by elementary analyses, IR, 1H NMR and MS spectra. Their spectral properties were also discussed.

Key words: 1,2,4-Triazolo[3,4-b]-1,3,4-thiadiazole, Synthesis, Spectral properties

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