Synthesis of Pyrazolyl-heterocycles and Their Fungicidal Activities

Abstract

Abstract: Aseries of pyrazolyl heterocycles, including1,3,4thiodiazoles, 1,3,4-oxadiazoles and 1,3,4-triazoles were synthesized from 4-nitro pyrazole formhydrazide. The structures of all new compounds were confirmed by ¹H NMRand elementary analysis. Their fungicidal activity was evaluated against Rhizoctonia solani. Structure activity relationships for the screened compounds were evaluated and discussed. It was found that some compounds showed a higher fungicidal activity and systematic activity.

Key words: Pyrazole, 1,3,4-Thiodiazole, 1,3,4-Oxadiazole, 1,3,4-Triazole, Fungicidal activity

CLC Number:

O626

TrendMD:

ZHAO WeiGuang, CHEN Han-Song, LI Zheng-Ming, HAN Yu-Fen, YAN Han, LAI Jun-Ying, WANG Su-Hua . Synthesis of Pyrazolyl-heterocycles and Their Fungicidal Activities[J]. Chem. J. Chinese Universities, 2001, 22(6): 939.

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Synthesis of Pyrazolyl-heterocycles and Their Fungicidal Activities

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