Preparation and Evaluation of Aza Crown Ether Bonded Silica for High-performance Liquid Chromatography

Abstract

Abstract: 3-(Aza-18-crown-6)propylsily bonded silica stationary phase for high performance liquid chromatography was prepared via two-step solid-liquid reaction as follows: porous silica(5～7 μm) was activated using γ-chloropropyl triethoxysilane, then reacted with sodium secondary amine salt of monoaza-18-crown-6. The bonded stationary phase shows a good complexing ability with sodium and potassium ions. The chromatographic behavior of disubstituted benzenes and amino acids was investigated on the bonded stationary phase with various mobile phases.

Key words: HPLC, Bonded silica stationary phase, Aza crown ether

CLC Number:

O652.63

TrendMD:

FENG Yu-Qi, GONG Yin-Han, DA Shi-Lu  . Preparation and Evaluation of Aza Crown Ether Bonded Silica for High-performance Liquid Chromatography[J]. Chem. J. Chinese Universities, 1998, 19(5): 720.

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Preparation and Evaluation of Aza Crown Ether Bonded Silica for High-performance Liquid Chromatography

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