Stereochemical Effect in Mass Spectrometry(19)──Determination of the Optical Purity of α-Phenylethylamine by Mass Spectrometry

Chem. J. Chinese Universities ›› 1996, Vol. 17 ›› Issue (9): 1421.

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Stereochemical Effect in Mass Spectrometry(19)──Determination of the Optical Purity of α-Phenylethylamine by Mass Spectrometry

WU Yi-Nan^1,2, TU Ya-Ping^1,2, PAN Yuan-Jiang^1,2, CHEN Yao-Zu^1,2, CUI Meng³, SONG Feng-Rui³, LIU Shu-Ying³

1. Department of Chemistry, Zhejiang Uriversity, Hangzhou, 310027;
2. State Key Laboratory of Applied Organic Chemistry, Lanzhou University;
3. Changchun Institute of Applied Chemistry, Chinese Academy of Sciences

Received:1995-10-15 Online:1996-09-24 Published:1996-09-24

Abstract

Abstract: It is found that in the fast atom bombardment(FAB) mass spectra R-α-phenylethylamine and S-α-phenylethylamine can be clearly distinguished by S-1,1'-binaph thyl-2,2'-Jiylhydrogenphosphate(S-BNP).Mixture of R-α-phenylethylamine and S-αphenylethylamine also be tested and the relative abundance of the characteristic ion of mixture is related to the composition of the mixtute.We have therefore proposed a possible method to determine the optical purity of α-phenylethyiamine.

Key words: Enantiomer, Optical purity, Determination by MS

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WU Yi-Nan, TU Ya-Ping, PAN Yuan-Jiang, CHEN Yao-Zu, CUI Meng, SONG Feng-Rui, LIU Shu-Ying. Stereochemical Effect in Mass Spectrometry(19)──Determination of the Optical Purity of α-Phenylethylamine by Mass Spectrometry[J]. Chem. J. Chinese Universities, 1996, 17(9): 1421.

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Stereochemical Effect in Mass Spectrometry(19)──Determination of the Optical Purity of α-Phenylethylamine by Mass Spectrometry

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