Chem. J. Chinese Universities ›› 1996, Vol. 17 ›› Issue (8): 1188.

• Articles • Previous Articles     Next Articles

Synthesis of Heteropoly Blue of Praseodymium Tungstophosphte with Keggin Structure and Studies on Their Anti-HIV Activity

LIU Shu-Xia1, LIU Yan-Yong1, WANG En-Bo1, ZENG Yi2, LI Ze-Lin2   

  1. 1. Department of Chemistry, Northeast Normal University, Changchu 130024;
    2. Chinese Academy of Preventive Medicine, Beijing
  • Received:1995-08-21 Online:1996-08-24 Published:1996-08-24

Abstract: e-and 4e-Heteropoly bule compounds of praseodymium tungstophosphate with Keggin structure were synthesized for the first time using control-potential electrolysis method, IR, UV-Vis and 31P NMRspectra were used to characterize their structures.The test of checking proliferation of MT-4 cells and their anti-HIVactivities show that these heteropoly blue compounds of praseodymium salts with Keggin structure have fairly low cell toxicity and relatively high anti-HIVactivity, The TI50 of Pr(2)and Pr(4)are 66 and 70,which demonscrate that their anti-HIVactivities are better than those of PM-29.

Key words: Tungstophosphrie heteropoly blue, Praseodymium salt, Synthesis, Anti-HIV activity

TrendMD: