Studies on Synthesis for 1-Phenyl-3-methyl-4-(β-benzoylocetyl) pyrazolone-5 and Its Equilibrium of Keto-Enol Tautomerism

Abstract

Abstract: Anew compound, 1-Phenyl-3-methyl-4-(β-benzoylocetyl) pyrazolone-5 was synthesized by acylation. Its composition and molecular weight were confirmed by elemental analysis and mass spectrometry. The presence of the enol-chelating form at the side chain, 4-(β-benzoyllacetyl) was indicated by IR, UV and ¹³C NMR, and also confirmed by X-ray crystal analysis. The equilibrium of keto-enol tautomerism for this compound was investigated by UVspetra and also by ¹H NMR emphatically.

Key words: Compound, Synthesis, Keto-enol tautomcrism, Single crystal

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Kong Bi-xia, Li Yuan-ying, Yang Yan-sheng . Studies on Synthesis for 1-Phenyl-3-methyl-4-(β-benzoylocetyl) pyrazolone-5 and Its Equilibrium of Keto-Enol Tautomerism[J]. Chem. J. Chinese Universities, 1991, 12(6): 719.

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Studies on Synthesis for 1-Phenyl-3-methyl-4-(β-benzoylocetyl) pyrazolone-5 and Its Equilibrium of Keto-Enol Tautomerism

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