Chem. J. Chinese Universities ›› 2024, Vol. 45 ›› Issue (7): 20240169.doi: 10.7503/cjcu20240169

• Polymer Chemistry • Previous Articles     Next Articles

Piezoelectric Effect of Polyether Ether Ketone Fibers Loaded with Bismuth Oxide Stimulating Osteogenic Differentiation

LIANG Luxian1, SONG Anqi1, ZHOU Yang1, SUN Ping1,2(), WANG Deqiang1(), WEI Jie1()   

  1. 1.Key Laboratory for Ultrafine Materials of the Ministry of Education,School of Materials Science and Engineering,East China University of Science and Technology,Shanghai 200237,China
    2.Department of Orthopaedics,Shanghai Eighth People’s Hospital,Shanghai 200235,China
  • Received:2024-04-04 Online:2024-07-10 Published:2024-05-28
  • Contact: WEI Jie E-mail:sunping1127@126.com;Derek_wang@ecust.edu.cn;jwei@ecust.edu.cn
  • Supported by:
    the National Natural Science Foundation of China(32171340)

Abstract:

Oxygen-vacancy bismuth oxide(BiO2‒x ) with excellent piezoelectric property was prepared by ultrasonic peel method and loaded on polyether ether ketone(PEEK) fiber by using chlorogenic acid. A kind of rotator cuff patch material with piezoelectric effect was designed, and its effects on macrophage polarization and osteoblast behavior were studied. The results showed that after loading BiO2‒x, not only the surface properties(roughness, hydrophilicity, and surface energy, etc.) of PEEK fibers were obviously improved, but also the piezoelectric properties were significantly enhanced(piezoelectric coefficient of 3.8 pC/N, output voltage of 0.97 V and output current of 575.6 μA). The patch material not only promoted the anti-inflammatory M2 macrophage polarization, but also promoted the adhesion, proliferation, and osteogenic differentiation of osteoblasts. The patch material has potential application for repairing rotator cuff tear.

Key words: Polyether ether ketone fiber, Surface modification, Piezoelectric effect, Macrophage polarization, Osteoblast differentiation

CLC Number: 

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