Comparative Chromatographic Method for Rapid Screening of Target Ionic Liquids†

doi:10.7503/cjcu20131288

Abstract

Abstract:

Analytical chemists learn the polarity of chromatographic stationary phase by testing the Rohrschneider-McReynolds constants in chromatographic columns, while chemical engineers acquire the selectivity and solubility of solvents by determining solubility parameters. However, in evaluating the properties of ionic liquids, they are not as useful as in general solvents. Sometimes the probe molecules have no peaks, and sometimes the solubility parameters calculated are not as what we predict. In order to overcome the shortages of the existing methods, a comparative chromatographic method was established, in which a well-known ionic liquid was used as a reference stationary liquid into the reference column, and new design ionic liquids as a sample stationary liquid filling into the sample column. With 7 solvents(n-hexane, ethyl acetate, benzene, 2-ketone, pyridine, n-butanol and nitro propane) as probe molecules, the adjusted retention time and asymmetry factor as the index, the target ionic liquids can be selected.

Key words: Comparative chromatography method, Ionic liquids reference column, Ionic liquids sample column, Probe molecules

CLC Number:

O657.7

TrendMD:

LIU Chaoqing, WANG Xiaoyi, ZHAO Jingqiang, CHEN Chunyue. Comparative Chromatographic Method for Rapid Screening of Target Ionic Liquids^†[J]. Chem. J. Chinese Universities, 2014, 35(5): 954.

Figures/Tables 5

References 27

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Column	Stationary phase	Source
Reference column	Chromosorb102+[BMIM][NTF₂]^a	Lanzhou Institute of Physical Chemistry, Chinese Academy of Sciences
Sample column 1	Chromosorb102 +[XMIM][NTF₂] ^b	Prepared in the laboratory, purity>98%
Sample column 2	Chromosorb102+[YMIM][NTF₂] ^c	As above

Column	Stationary phase	Source
Reference column	Chromosorb102+[BMIM][NTF₂]^a	Lanzhou Institute of Physical Chemistry, Chinese Academy of Sciences
Sample column 1	Chromosorb102 +[XMIM][NTF₂] ^b	Prepared in the laboratory, purity>98%
Sample column 2	Chromosorb102+[YMIM][NTF₂] ^c	As above

Solute	Molecular weight	Boiling point/℃	Dielectric constant, ε	Dipolar moment, 10^-3 μ/(C·m)	Refractive index, n	Polarity	Viscosity
Hexane	86.17	68.7	2.02	0	1.375	0.06	0.33
Ethyl acetate	88.10	77.2	6.02	1.78	1.372	4.3	0.45
Benzene	78.11	80.1	2.28	0	1.501	3.0	0.65
2-Pentanone	86.13	102.3	15.4	9.0	1.391	4.7
Pyridine	79.10	115.5	12.9	7.9	1.510	5.3	0.97
Butanol	74.12	117.7	17.8	5.8(1.66)	1.398	3.7	2.95
Nitropropane	89.09	131.2	35.8	13	1.402	6.0	0.67

Solute	Molecular weight	Boiling point/℃	Dielectric constant, ε	Dipolar moment, 10^-3 μ/(C·m)	Refractive index, n	Polarity	Viscosity
Hexane	86.17	68.7	2.02	0	1.375	0.06	0.33
Ethyl acetate	88.10	77.2	6.02	1.78	1.372	4.3	0.45
Benzene	78.11	80.1	2.28	0	1.501	3.0	0.65
2-Pentanone	86.13	102.3	15.4	9.0	1.391	4.7
Pyridine	79.10	115.5	12.9	7.9	1.510	5.3	0.97
Butanol	74.12	117.7	17.8	5.8(1.66)	1.398	3.7	2.95
Nitropropane	89.09	131.2	35.8	13	1.402	6.0	0.67

Column	t_r'/min
Column	Hexane	Ethyl acetate	Benzene	2-Pentanone	Pyridine	Butanol	Nitropropane
Reference column	0.359	4.673	4.168	11.380	23.425	10.055	27.435
Sample column 1	0.301	6.506	4.354	14.072		14.184	16.570
Sample column 2	0.196	3.909	3.063	9.531		9.531	22.399