Crystal Structure, Spectroscopic Properties and Antibacterial Activity of Binuclear Lead Complex with O, O'-Di(p-methylphenyl)dithiophosphate

doi:10.7503/cjcu20120736

Abstract

Abstract:

A new binuclear lead complex Pb₂[S₂P(OC₆H₄Me-p)₂]₂[μ-S₂P(OC₆H₄Me-p)₂]₂ was synthesized and characterized, the antibacterial activities of the raw material (p-MeC₆H₄O)₂PS₂NH₂Et₂ and the complex were studied. The complex crystallized in triclinic, P1 space group with the cell parameters: a=1.06393(6) nm, b=1.15005(6) nm, c=1.45006(5) nm, α=94.109(3)°, β=98.833(4)°, γ=109.242(5)°, V=1.64099(14) nm³, D_c=1.671 Mg/m³, Z=1, F(000)=808, μ(Mo Kα)=5.523 mm^-1, S=1.024, R₁=0.0596, wR₂=0.1464[I > 2σ(I)]. The crystal structure study shows that the complex contains two chelating anisobidentate and two bridging tridentate (p-MeC₆H₄O)₂PS₂^- ligands. Each lead atom is in a distorted ψ-pentagonal bipyramidal geometry by five sulfur atoms from three (p-MeC₆H₄O)₂PS₂^- ligands, an aryl group of one of bridging (p-MeC₆H₄O)₂PS₂^- ligand, and a lone pair of stereochemically active electron originating from the lead atom, in which four sulfur atoms and a lone electron pair of lead locate in the equatorial positions, and a sulfur and an aryl group in the axial positions[the Pb1—S bond lengths rang from 0.2750 to 0.3257 nm, the distance of Pb1…C_gⁱ is 0.3365(2) nm, and the S1—Pb1—C_gⁱ angle is 173.79(5)°]. The two bridging (p-MeC₆H₄O)₂PS₂^- ligands each bridges two lead atoms to form an chair conformation of eight-membered ring [Pb₂S₄P₂]. The complex is stable up to over 281.7℃. The bioactivity test shows that both the raw material and complex can inhibit Staphylococcus, E. Coli, and B. Subtilis and the complex exhibited the higher antibacterial activity compared with the raw material.

Key words: O,O'-Dialkyldithiophosphate, Pb complex, Crystal structure, Spectroscopic property, Antibacterial activity

CLC Number:

O614.43

TrendMD:

WANG Yan-Mei, CAI Shu-Lan, HE Lin-Xin, ZHU Sha-Sha, WANG Jun, LIN Xiao, LI Yu-Long, ZOU Li-Ke. Crystal Structure, Spectroscopic Properties and Antibacterial Activity of Binuclear Lead Complex with O, O'-Di(p-methylphenyl)dithiophosphate[J]. Chem. J. Chinese Universities, 2013, 34(1): 30.

References

Related Articles 15

[1]	LIU Qingqing, WANG Pu, WANG Yongshuai, ZHAO Man, DONG Huanli. Synthesis and Topochemical Polymerization Study of Naphthalene/perylene Imides Substituted Diacetylene Derivatives [J]. Chem. J. Chinese Universities, 2022, 43(6): 20220091.
[2]	SHI Naike, ZHANG Ya, SANSON Andrea, WANG Lei, CHEN Jun. Uniaxial Negative Thermal Expansion and Mechanism in Zn（NCN） [J]. Chem. J. Chinese Universities, 2022, 43(6): 20220124.
[3]	HU Haocheng, LI Wenli, ZHANG Jianing, LIU Yubo. Extraction， Structure Characterization and Biological Activities of Oligosaccharides from Auricularia heimuer [J]. Chem. J. Chinese Universities, 2021, 42(8): 2465.
[4]	YUE Shengli, WU Guangbao, LI Xing, LI Kang, HUANG Gaosheng, TANG Yi, ZHOU Huiqiong. Research Progress of Quasi-two-dimensional Perovskite Solar Cells [J]. Chem. J. Chinese Universities, 2021, 42(6): 1648.
[5]	TIAN Xia,YANG Fuqun,YUAN Wei,ZHAO Lei,YAO Lei,ZHEN Xiaoli,HAN Jianrong,LIU Shouxin. Synthesis, Structure and Recognition Properties of Macrocyclic Crown Ethers with Oxadiazole ^† [J]. Chem. J. Chinese Universities, 2020, 41(3): 490.
[6]	LIU Dongmei,SU Yajing,LI Shanshan,XU Qiwei,LI Xia. Transition Metal Coordination Polymers Constructed by 4-(4-Carboxyphenoxy)isophthalic Acid: Synthesis, Crystal Structure, Fluorescence Sensing and Photocatalysis ^† [J]. Chem. J. Chinese Universities, 2020, 41(2): 253.
[7]	QIN Liulei,LIU Yang,GUAN Xiaoqin,ZHENG Xiaoyuan,ZHANG Ziyu,LIU Zunqi. Synthesis and Switchable Dielectric Properties of an Inorganic-organic Hybrid Complex [H₂(DABCO)CuCl₄]·H₂O ^† [J]. Chem. J. Chinese Universities, 2020, 41(1): 70.
[8]	MAO Long, LIU Yuejun, FAN Shuhong. Preparation and Properties of Polypyrrole Modified Layered Clay/poly(ε-caprolactone) Antibacterial Nanocomposites [J]. Chem. J. Chinese Universities, 2019, 40(8): 1726.
[9]	LI Pu,CHEN Ying,XIA Rongjiao,GUO Tao,ZHANG Min,JIANG Shichun,ANG Xu,HE Ming,XUE Wei. Synthesis and Biological Activities of Myricetin Derivatives Containing Quinoxaline^† [J]. Chem. J. Chinese Universities, 2019, 40(5): 909.
[10]	LI Bing,WANG Xuemin,BAI Fengying,LIU Shuqing. Synthesises, Structures and Antibacterial Activities of a Series of Rare Earth Nitrogen Heterocyclic Complexes^† [J]. Chem. J. Chinese Universities, 2019, 40(4): 632.
[11]	WANG Dongmei,LIU Zihua,LI Guanghua,LIU Yunling,LI Chunxia. Synthesis, Structure and Fluorescent Property of Indium-based Bimetallic Metal-organic Frameworks^† [J]. Chem. J. Chinese Universities, 2018, 39(9): 1886.
[12]	WAN Jinlin, WU Shouqun, GAN Yiyuan, MENG Jiao, WANG Zhenchao, OUYANG Guiping. Synthesis and Antibacterial Activities Evaluation of Chalconesemicarbazone Derivatives Bearing 1,3,4-Thiadiazole Moiety^† [J]. Chem. J. Chinese Universities, 2018, 39(8): 1683.
[13]	JIA Yunjing, SHI Wensi, HU Feiliu, ZHU Huajie, LIU Li, MA Zhengyue. Cytotoxic Activity of Trichothecene Compounds and Derivatives from Myrothecium sp.^† [J]. Chem. J. Chinese Universities, 2018, 39(8): 1668.
[14]	TIAN Huan, ZHANG Menglong, WANG Lisha, TONG Bihai, ZHAO Zhuo. Synthesis of 4,13-Dithio Benzene and-18-Crown-6 and Its Selective Extractability on A $g + †$ [J]. Chem. J. Chinese Universities, 2018, 39(6): 1191.
[15]	ZHU Lei,HAN Junyan,CHANG Haizhen,QIU Yuyuan,ZHANG Yanan,PENG Danni,HU Wei,MIAO Shaobin. Different Pathways for the Cyclocondensation Reactions of 1,2-Diamine and 1,2-Diketone^† [J]. Chem. J. Chinese Universities, 2018, 39(12): 2686.