高等学校化学学报

高等学校化学学报

• 研究论文 • 上一篇    下一篇

正辛基-L-羟基脯氨酸萃取苯丙氨酸的机理及性能

崔玉1, 尹少宏1, 孙国新1, 田晓强1,2, 崔玉花1   

    1. 济南大学化学化工学院, 济南 250022;
    2. 中国兵器工业集团第五三研究所, 济南 250031
  • 收稿日期:2007-10-10 修回日期:1900-01-01 出版日期:2008-05-10 发布日期:2008-05-10
  • 通讯作者: 孙国新

Extraction Mechanism and Property of Phenyl Alanine with n-Octyl-L-hydroxyproline

CUI Yu1, YIN Shao-Hong1, SUN Guo-Xin1*, TIAN Xiao-Qiang1,2, CUI Yu-Hua1   

    1. School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China;
    2. Institute 53 of China North Industries Group Corporation, Jinan 250031, China
  • Received:2007-10-10 Revised:1900-01-01 Online:2008-05-10 Published:2008-05-10
  • Contact: SUN Guo-Xin

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摘要： 研究了正辛基-L-羟基脯氨酸萃取苯丙氨酸的性能和机理, 详细考察了起始氨基酸的浓度、萃取剂的浓度、酸度、铜离子的浓度、温度等因素分别对D-和L-苯丙氨酸萃取性能的影响. 随着起始氨基酸pH值的增大, 萃取分配比D也增大, 对映体分离系数α可以达到2. 萃取反应为吸热反应, 升高温度有利于反应的进行. 表征了萃合物的组成, 推测萃合物的结构为1∶1∶1型的三元配合物. 研究结果为苯丙氨酸的萃取拆分提供了理论依据.

关键词: 正辛基-L-羟基脯氨酸, 萃取, 苯丙氨酸

Abstract: A novel chiral extractant n-octyl-L-hydroxyproline was synthesized. The extraction mechanism and property of D- or L-phenyl alanine with n-octyl-L-hydroxyproline with n-octane and n-octanol(volume ratio, 7∶3) as the diluent was investigated. The effect of concentrations of extractant and copper ion and pH on the extraction of phenyl alanine was studied. The influence of temperature on the extraction shows that the extraction is endothermic reaction. The extracted species were characterized and the structure was suggested. This result will be helpful for the further study on extracting and separating D,L-phenyl alanine.

Key words: n-Octyl-L-hydroxyproline, Extraction, Phenyl alanine

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