高等学校化学学报 ›› 2010, Vol. 31 ›› Issue (6): 1158.

• 研究论文 • 上一篇    下一篇

BrΦnsted酸性离子液体[HSO3-bpy][HSO4]催化合成β-吲哚酮

余传继, 刘晨江   

  1. 新疆大学化学化工学院, 石油天然气精细化工教育部重点实验室, 乌鲁木齐 830046
  • 收稿日期:2009-08-31 出版日期:2010-06-10 发布日期:2010-06-10
  • 通讯作者: 刘晨江, 男, 博士, 副教授, 主要从事有机合成方法学的研究. E-mail: pxylcj@126.com
  • 基金资助:

    国家自然科学基金(批准号: 20862016)资助.

Synthesis of β-Indolylketones Catalyzed by BrΦnsted Acidic Ionic Liquid [HSO3-bpy][HSO4]

YU Chuan-Ji, LIU Chen-Jiang*   

  1. Key Laboratory of Oil and Gas Fine Chemicals, Ministry of Education, School of Chemistry and Chemical Engineering, Xinjiang University, Urumqi 830046, China
  • Received:2009-08-31 Online:2010-06-10 Published:2010-06-10
  • Contact: LIU Chen-Jiang. E-mail: pxylcj@126.com
  • Supported by:

    国家自然科学基金(批准号: 20862016)资助.

摘要:

以BrΦnsted酸性离子液体[HSO3-bpy][HSO4]为催化剂, 将吲哚或取代吲哚与α,β-不饱和酮在乙腈中于80 ℃下反应3 h, 以92%~98%的产率制备了一系列的β-吲哚酮. 该方法简便易行且产率高. 催化剂离子液体对环境友好, 并可循环使用.

关键词: BrΦnsted酸性离子液体; α,β-不饱和酮; β-吲哚酮

Abstract:

The BrΦnsted acidic ionic liquid [HSO3-bpy][HSO4] was reported as an efficient catalyst for the Michael addition reaction of indoles to α,β-unsaturated ketones. The reactions were carried out at 80 ℃ in acetonitrile for 3 h with stirring. Satisfactory results were obtained, with excellent yields and a simple experimental procedure. In addition, the ionic liquid was environmentally friendly and reused for three times without any noticeable decrease in the catalytic activity.

Key words: Brnsted acidic ionic liquid; α,β-Unsaturated ketone; β-Indolylketone

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