高等学校化学学报

高等学校化学学报 ›› 2006, Vol. 27 ›› Issue (2): 352.

• 研究论文 • 上一篇    下一篇

非手性席夫碱-异丙氧基铝引发外消旋丙交酯的立构选择性聚合

杨永坤, 汤朝晖, 庞烜, 杜鸿志, 陈学思, 景遐斌   

  1. 中国科学院长春应用化学研究所, 高分子物理和化学国家重点实验室, 中国科学院研究生院,  长春 130022
  • 收稿日期:2005-04-08 出版日期:2006-02-10 发布日期:2006-02-10
  • 通讯作者: 陈学思(1959年出生), 男, 博士, 研究员, 博士生导师, 主要从事医用高分子和生物降解高分子研究. E-mail: xschen@ciac.jl.cn
  • 基金资助:

    国家自然科学基金(批准号： 50273038, 20274048, 50373043)和国家杰出青年基金(批准号： 50425309)资助.

Stereoselective Polymerization of rac-Lactide Initiated by Achiral Schiff-base Isopropoxide Aluminum Complex

YANG Yong-Kun,  Tang-Chao-Hui,  PANG-Hui,  Du-Hong-Zhi,  Chen-Xue-Si,  Jing-Xia-Bin   

  1. State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of  Applied Chemistry,
    Chinese Academy of Sciences, Graduate School of Chinese Academy of Sciences, Changchun 130022, China
  • Received:2005-04-08 Online:2006-02-10 Published:2006-02-10
  • Contact: Chen-Xue-Si,E-mail: xschen@ciac.jl.cn

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被引次数

31

摘要：

摘要以非手性的席夫碱-异丙氧基铝(Ⅱ)引发外消旋丙交酯(rac-LA)的立构选择性聚合. 其聚合动力学研究结果表明, 聚合反应对于单体符合一级反应动力学. 所得聚合物的数均分子量与单体转化率成正比, 并且分子量分布很窄， 表明该聚合反应具有良好的可控性. 此外所得的聚外消旋乳酸是tm为179 ℃的结晶性聚合物. 13C NMR和同核去偶1H NMR谱表明, 所得的聚乳酸是一种立构嵌段聚合物, 平均嵌段长度为11个乳酸单元.

关键词: 关键词非手性席夫碱-异丙氧基铝; 外消旋丙交酯; 立构选择性聚合; 可生物降解高分子

Abstract:

Abstract An achiral Schiff-base isopropoxide aluminum complex(Ⅱ) was used for the stereoselective ring-opening polymerization of rac-lactide. The kinetics studies indicated that rac-lactide polymerization was first order kinetics to monomer concentration. There was linear relationship between the monomer conversion and molecular weights(Mn) of the polymer with a narrow molecular distribution. These phenomena indicated that the polymerization was well controllable. Moreover, the obtained poly(rac-lactide) was crystalline polymer with relative high tm(179 ℃). 13C NMR and homonuclear decoupled 1H NMR spectra revealed that the polymerization of rac-lactide initiated by complex(Ⅱ) resulted in the isotactic stereoblock polymer, which contained blocks with an average of 11 units of enantiomerically pure lactic acid.

Key words: KeywordsAchiral Schiff-base isopropoxide aluminum complex; rac-Lactide; Stereoselective polymerization;Biodegradable polymer

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