高等学校化学学报

高等学校化学学报 ›› 2005, Vol. 26 ›› Issue (6): 1052.

• 研究简报 • 上一篇    下一篇

中红外光谱无创伤检测血糖新方法

赵莹1,2, 张元福1, 杨丽敏1, 徐怡庄1, 翁诗甫1, 杨展澜1, 武惠忠3, 周维金1, 徐端夫2, 吴瑾光1   

  1. 1. 北京大学化学与分子工程学院, 北京100871;
    2. 中国科学院化学研究所, 高分子物理与化学国家重点实验室, 北京100080;
    3. 北京瑞利分析仪器公司, 北京100015
  • 收稿日期:2004-08-10 出版日期:2005-06-10 发布日期:2005-06-10
  • 通讯作者: 吴瑾光(1934年出生),女,教授,博士生导师,从事无机化学和振动光谱研究.E-mail:wjg@pku.edu.cn E-mail:wjg@pku.edu.cn
  • 基金资助:

    国家自然科学基金(批准号:30371604,50203001);国家重大基础研究前期专项(批准号:2002CCA01900);教育部博士点基金(批准号:20030001069)资助.

A Novel Non-invasive Method of Blood Glucose MeasurementUsing FT-Mid-IR Spectroscopy

ZHAO Ying1,2, ZHANG Yuan-Fu1, YANG Li-Min1, XU Yi-Zhuang1, WENG Shi-Fu1, YANG Zhan-Lan1, WU Hui-Zhong3, ZHOU Wei-Jin1, XU Duan-Fu2, WU Jin-Guang1   

  1. 1. College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China;
    2. State Key Laboratory of Polymer Physics and Chemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China;
    3. Beijing Rayleigh Analytical Instrument Corporation, Beijing 100015, China
  • Received:2004-08-10 Online:2005-06-10 Published:2005-06-10

PDF (PC)

被引次数

37

关键词: 红外光谱, 血糖, 糖尿病

Abstract: The blood glucose concentrations of volunteers from diabetes patients and healthy adults(all patients and volunteer who joined this experiment gave their consents) were measured by using a modified WQF-200 FTIR spectrometer with a newly designed ATR accessory. The results of this method are in good agreement with the clinical blood detection. The determination basis for this technique from the physiological point of view are also discussed based on the experimental results, which indicated that the glucose components measured by the FT-Mid-IR-ATR are from the secretions on the skin and glucose components within the body. The glucose components in both sources exhibit a linear relationship with blood glucose concentration within the body. All the results demonstrated that blood glucose concentration can be measured in a convenient, rapid and non-invasive way using ATR-FTIR spectroscopy, which is suitable for developing of a new technique to monitor the continuous variation of blood glucose concentration of diabetes patients in real time.

Key words: IR Spectroscopy, Blood glucose, Diabetes

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