高等学校化学学报 ›› 2002, Vol. 23 ›› Issue (5): 958.

• 研究简报 • 上一篇    下一篇

短杆菌肽在十八烷基硫醇自组装单层膜上的通道行为

郭继东1, 邢巍1, 陆天虹1, 杨辉2   

  1. 1. 中国科学院长春应用化学研究所, 长春 130022;
    2. 南京师范大学化学系, 南京 210097
  • 收稿日期:2000-06-21 出版日期:2002-05-24 发布日期:2002-05-24
  • 通讯作者: 陆天虹(1945年出生),男,研究员,博士生导师,从事生物电化学及燃料电池研究.E-mail:tianhonglu@263.net E-mail:tianhonglu@263.net
  • 基金资助:

    江苏省教育委员会和厦门大学固体表面物理化学国家重点实验室资助.

The Channel Behavior of Gramicidin in Mercaptan Self-assembled Monolayer Membrane

GUO Ji-Dong1, XING Wei1, LU Tian-Hong1, YANG Hui2   

  1. 1. Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China;
    2. Department of Chemistry, Nanjing Normal University, Nanjing 210097, China
  • Received:2000-06-21 Online:2002-05-24 Published:2002-05-24

关键词: 短杆菌肽, 自组装单分子层膜, 离子通道

Abstract: The present paper reports the channel behavior of gramicidin in mercaptan self-assembled mono-layer on the surface of the gold electrode by using the electrochemical method.The current responses to K+ ions and the electrode potential for the gold electrodes modified .with self-assembled mercaptan mono-layer incorporating and not incorporating gramicidin Dwere compared.The results firstly indicated that gramicidin Dmolecules can be incorporated into the mercaptan monolayer assembled on the surface of the gold electrode and form monovalent ion channel.Amechanism of the phenomenon was proposed.

Key words: Gramicidin, Self-assembled monolayer, Ion channel

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