高等学校化学学报 ›› 2001, Vol. 22 ›› Issue (7): 1108.

• 研究快报 • 上一篇    下一篇

溶胶-凝胶法制备丙二酰胺型二氧大环多胺用作开管柱电色谱固定相的研究

曾昭睿, 谢传辉, 王园朝, 管娜, 付恩琴, 程介克   

  1. 武汉大学化学系, 武汉 430072
  • 收稿日期:2000-12-26 出版日期:2001-07-24 发布日期:2001-07-24
  • 通讯作者: 曾昭睿(1947年出生),女,副教授,主要从事色谱新型固定相的研究.现在咸宁师范专科学校化学系工作.
  • 基金资助:

    国家自然科学基金(批准号:29975021);湖北省自然科学基金(批准号:20500132)

Sol-gel-derived Macrocyclic Dioxopolyamine Stationary Phase for Open-tubular Electrochromatography

ZENG Zhao-Rui, XIE Chuan-Hui, WANG Yuan-Chao, GUAN Na, FU En-Qin, CHENG Jie-Ke   

  1. Department of Chemistry, Wuhan University, Wuhan 430072, China
  • Received:2000-12-26 Online:2001-07-24 Published:2001-07-24

关键词: 毛细管电色谱, 丙二酰胺型二氧大环多胺, 溶胶-凝胶技术

Abstract: This paper covers the preparation of a sol-gel-derived macrocyclic dioxopolyamine(1,4,7,10-tetraazaclotridecane-11,13-dione) stationary phase for open tubular capillary electrochromatography(OTCEC). The sol-gel-derived macrocyclic dioxopolyamine capillary columns have shown improved separations of neurotransmitters, isomeric nitrophenols, isomeric dihydroxybenzenes, isomeric aminophenols, isomeric diaminobenzenes and three ortho-halogen anilines, in comparison with those of untreated capillaries. The characteristics of the solgel-derived macrocyclic dioxopolyamine capillary columns are compared with the capillary column modified with the macrocyclic dioxopolyamine by chemically bonded method after etching. The sol-gel method provided a porous silica material with stationary phase in place within the same experimental procedure. This provided speedy fabrications of high-efficiency columns with high surface area and improved phase ratio. We achieved high efficiencies of 60000-340000 plates/m for the various isomeric compounds. The reproducibility migration time and the plate number were pretty good.

Key words: Open tubular electrochromatography, Macrocyclic dioxopolyamine, Sol-gel

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