高等学校化学学报 ›› 2000, Vol. 21 ›› Issue (11): 1655.

• 研究简报 • 上一篇    下一篇

聚糖联乙炔类脂仿生膜与大肠杆菌的识别作用研究

范翊1, 李亚军1, 张立功2, 施雨露3, 蒋大鹏2   

  1. 1. 中国科学院长春物理研究所, 长春 130021;
    2. 中国科学院激发态物理开放实验室, 长春 130021;
    3. 白求恩医科大学基础医学院, 长春 130021
  • 收稿日期:1999-10-28 出版日期:2000-11-24 发布日期:2000-11-24
  • 通讯作者: 范翊(1967年出生),女,助理研究员,主要从事有序薄膜的分子识别功能特性研究.E-mail:lbfilm@public.cc.jl.cn E-mail:lbfilm@public.cc.jl.cn
  • 基金资助:

    国家自然科学基金(批准号:69671001);国家自然科学基金重点项目(批准号:69831010)资助

The Study on Recognition of Polydiacetylene Functionalized with Mannopyranoside Mimic Membrance for Escherichia Coli

FAN Yi1, LI Ya-Jun1, ZHANG Li-Gong2, SHI Yu-Lu3, JIANG Da-Peng2   

  1. 1. Changchun Institute of Physics, Chinese Academy of Sciences, Changchun 130021, China;
    2. Lab.Excited State Processes, Chinese Academy of Sciences, Changchun
  • Received:1999-10-28 Online:2000-11-24 Published:2000-11-24

关键词: 糖脂, Langmuir-Blodgett薄膜, 肠道杆菌, 识别作用

Abstract: People has known that the recognition between cells and bacteria is related to the glycolipid, as a receptor on the cell surface. Diacetylene moiety in the hydrocarbon region can be cross linked by UV irradiation to form the corresponding polydiacetylene polymer. Color changes of polydiacetylenes have been known to occur in response to a variety of environmental perturbations such as heating, pH, mechanical stress or in the case of biosensor, due to the strong π-π* absorption of the conjugation backbone. In this report, polydiacetylene mixed with mannopyranoside monolayer is prepared by Langmuir Blodgett film technology, E.coli K12 adheres on the monolayer surface after gram strain. The result shows that the mannopyraoside could be recognitized by E.coli, but couldn 't be recognitized by O111 B4 and S.flexneri.

Key words: Glycolipid, Langmuir Blodgett film, E.coli, Recognition

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