高等学校化学学报 ›› 1997, Vol. 18 ›› Issue (1): 132.

• 研究简报 • 上一篇    下一篇

手性试剂TMPEA用于手性酮对映体纯度测定的研究

尤田耙, 胡小铭, 张大永   

  1. 中国科学技术大学化学系, 合肥, 230026
  • 收稿日期:1996-01-09 出版日期:1997-01-24 发布日期:1997-01-24
  • 通讯作者: 尤田耙, 50岁, 副教授.
  • 作者简介:尤田耙, 50岁, 副教授.
  • 基金资助:

    国家自然科学基金

Studies on the Utility of Chiral Reagent TMPEA for Measuring of Enantiomeric Purity of Chiral Ketones

Y0U Tian-Pa, HU Xiao-Ming, ZHANG Da-Yong   

  1. Department 0f Che, nistry, University of Science and Techn0logy of China, Hefei, 230O26
  • Received:1996-01-09 Online:1997-01-24 Published:1997-01-24

关键词: 手性试剂TMPEA, 测定, 手性酮, 对映体纯度

Abstract: Chiral amine TMPEAwas found to be useful in measuring of enantiomeric purityof chiraIketones.Four pairs of diastereomeric ketimines were prepared from R-(-)-TM-PEAand dl-TMPEAwith vari0us chiral ketones, the chemical shift differences between di-astereotopic protons (OCH3) were 0' 085-0.115, while fluorines (CF3) were 0' 17-0.45.

Key words: Chiral amine TMPEA, Measure, Chiral ketones, Enantiomeric purity

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