五种四环类抗生素的固体表面荧光法的研究

高等学校化学学报 ›› 1996, Vol. 17 ›› Issue (8): 1216.

五种四环类抗生素的固体表面荧光法的研究

解宏智, 董川, 刘长松, 赵丽霞, 杜学勤

山西大学化学系, 太原 030006

收稿日期:1995-07-26 出版日期:1996-08-24 发布日期:1996-08-24
通讯作者: 刘长松
作者简介:解宏智,男,27岁,硕士,助教.
基金资助:
国家自然科学基金;山西省自然科学基金

Studies on Solid Surface Room Temperature Fluorescence for Determination of Five Tetracycline Antibiotics

XIE Hong-Zhi, DONG Chuan, LIU Chang-Song, ZHAO Li-Xia, DU Xue-Qin

Depaftment of Chemistry, Shanxi University, Taiyuan 030006

Received:1995-07-26 Online:1996-08-24 Published:1996-08-24

摘要/Abstract

关键词: 固体表面荧光, 碱性降解, 四环类抗生素

Abstract: The solid surface room temperature fluorescence (SS-RTF)for determination of five tetracyclines on filter paper and the simultaneous determination of chlortetracycline(CTC) and tetracycline (TC) or CTC and oxytetracycline were described.Various factors of effect on RTFintensities of tetracyclines, such as pH condition, drying temperature and time of sample etc.were studied.The linear dynamic ranges, limit of detections and RSD were:2.1~205.0ng,1.3ng and 3.1 % for CTC;5.9~496.4ng,1.8ng and 2.6% for OTC;3.8~481.0 ng,3.6 ng and 2.8 % for TC;3.7~462.6ng,2.7 ng and 4.1 % for doxycycline (DOTC); 5.8~193.0ng,5.2 ng and 3.4% for methacycline (MTC), respectively.The recoveries of them in urine are from 95 % to 105%.

Key words: Solid surface room temperature flourescence, Alkaline degradation, Tetracyclines

TrendMD:

解宏智, 董川, 刘长松, 赵丽霞, 杜学勤. 五种四环类抗生素的固体表面荧光法的研究. 高等学校化学学报, 1996, 17(8): 1216.

XIE Hong-Zhi, DONG Chuan, LIU Chang-Song, ZHAO Li-Xia, DU Xue-Qin. Studies on Solid Surface Room Temperature Fluorescence for Determination of Five Tetracycline Antibiotics. Chem. J. Chinese Universities, 1996, 17(8): 1216.