高等学校化学学报

高等学校化学学报 ›› 1996, Vol. 17 ›› Issue (8): 1165.

• 论文 •    下一篇

二氯二苯基锡与单核苷酸配位作用的研究

李青山1, 杨频2, 王宏飞2, 郭茂林2, 万嘉铸3, 吴文士3   

  1. 1. 南京大学配位化学国家重点实验室, 南京 210093;
    2. 山西大学分子科学研究所, 太原 030006;
    3. 泉州华侨大学化学系, 泉州
  • 收稿日期:1995-08-28 出版日期:1996-08-24 发布日期:1996-08-24
  • 通讯作者: 杨频
  • 作者简介:李青山,男,30岁,博士研究生,讲师.
  • 基金资助:

    国家自然科学基金;南京大学配位化学国家重点实验室基金

Interactions of Diphenyltin Dichloride with Nucleotides

LI Qing-Shan1, YANG Pin2, WANG Hong-Fei2, GUO Mao-Lin2   

  1. 1. State Key Laboratory of Coordination Chemistry, Nanjing University, Nanjing 210093;
    2. Institute of Molecular Science, Shanxi University, Taiyuan, 030006;
    3. Department of Chemistry, Huaqiao University, Quanzhou
  • Received:1995-08-28 Online:1996-08-24 Published:1996-08-24

PDF (PC)

被引次数

5

摘要： 研究了二氯二苯基锡(Ph2SnCl2)与核酸的基本组成单元──单核苷酸在水相中的配位作用,并用热分析、傅利叶变换红外光谱和1H、31P超导核磁共振谱对新配合物Ph2Sn(5'-AMP)·H2O、Ph2Sn(5'-CMP)·H2O和Ph2Sn(5'-GMP)进行了详细的表征。结果表明,在配合物中锡仅与单核苷酸的磷酸根结合,给出了配合物的可能结构。

关键词: 二氯二苯基锡, 单核苷酸, 键合模式

Abstract: The interactions of diphenyltin dichloride(Ph2SnCl2)with nucleotides were studied in aqueous solutions.The new complexes of Ph2Sn(5'-AMP)·H2O, Ph2Sn(5'-CMP)·H2 and Ph2Sn(5'-GMP) were characterized by means of elementary analysis, thermal analysis, FTIR,1Hand 31PNMRspectra.In all the complexes, tin is only coordinated with the phosphate group of nucleotide, The possible structures of the new complexes are proposed.

Key words: Diphenyltin dichloride, Nucleotide, Binding mode

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