高等学校化学学报

高等学校化学学报 ›› 1996, Vol. 17 ›› Issue (4): 642.

• 论文 • 上一篇    下一篇

聚苯乙烯-g-聚氧乙烯接枝共聚物表面阻抗蛋白质吸附的研究

孙永红, 邱永兴, 俞小洁, 封麟先   

  1. 浙江大学高分子科学与工程系, 杭州 310027
  • 收稿日期:1995-04-02 出版日期:1996-04-24 发布日期:1996-04-24
  • 通讯作者: 孙永红,女,25岁,博士研究生.
  • 作者简介:孙永红,女,25岁,博士研究生.
  • 基金资助:

    国家自然科学基金;国家863青年基金

Studies on Protein-Resistance of AmphiphilicPolystyrene-g-Poly (ethylene oxide)Copolymers

SUN Yong-Hong, QIU Yong-Xing, YU Xiao-Jie, FENG Lin-Xian   

  1. Department of Polymer Science & Engineering, Zhejiang University, Hangzhou 310027
  • Received:1995-04-02 Online:1996-04-24 Published:1996-04-24

PDF (PC)

被引次数

12

摘要： 利用放射性碘标记技术研究了血浆蛋白质-缓冲溶液体系在聚苯乙烯-g-聚氧乙烯接枝共聚物表面的等温吸附和吸附动力学。材料表面蛋白质等温吸附量或平衡吸附量随表面PEO含量增加而下降;吸附量最低值小于0.25μg,cm-2;同时探讨了材料表面”梳状“结构对材料表面PEO侧链阻抗蛋白质性能的影响。

关键词: 聚苯乙烯-g-聚氧乙烯表面结构, 阻抗蛋白质, 血浆蛋白质等温吸附

Abstract: The adsorption isotherm and kinetics of simple plasma protein (human serum albumin immunoglobulin or fibrinogen)-buffer onto the surfaces of (PS-g-PEO) graft copolymers were investigated by radioiodine labelling technique.The reliability of IC1 labellingmethod was verified.It was discovered that the plateau protein adsorption amount usuallydecreased with surface PEOcontent of PS-g-PEOs increasing;the lowest protein plateau adsorption values were observed <0.25 μg.cm-2.The "comb-like" structure of model materials might be more fit for protein-resistant property of PEO side chains.

Key words: Surface structure of polystyrene-g-poly (ethylene oxide), Protein-resistance, Isothermal adsorption of plasma proteins

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