高等学校化学学报 ›› 1996, Vol. 17 ›› Issue (3): 427.

• 研究简报 • 上一篇    下一篇

(±)-Demethyl Salvicanol的首次全合成研究

王学超, 潘鑫复, 崔育新, 陈耀祖   

  1. 兰州大学化学系, 应用有机化学国家重点实验室, 兰州 730000
  • 收稿日期:1995-06-07 出版日期:1996-03-24 发布日期:1996-03-24
  • 通讯作者: 潘鑫复
  • 作者简介:王学超,男,27岁,博士.
  • 基金资助:

    国家自然科学基金

Studies on the Total Synthesis of (±)-Demethyl Salvicanol

WANG Xue-Chao, PAN Xin-Fu, CUI Yu-Xin, CHEN Yao-Zu   

  1. Department of Chemistry, State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000
  • Received:1995-06-07 Online:1996-03-24 Published:1996-03-24

关键词: DemethylSalvicanol, 全合成, 选择性还原, 锌促偶联反应

Abstract: Demethyl salvicanol,9(10→20)-abeo-8,11,13-triene-10β,11,12-triol,has been synthesized for the first time by using the intramolecular zinc-promoted coupling reaction of benzyl bromide with ketone and the alkylation of iodide 1-(2-iodoethvl)-3,4-dimethoxy-5-isopropylbenzene with ketone 5,5-dimethyl-2-cyclohexen-l-one as the key steps.

Key words: Demethyl salvicanol, Total synthesis, Selective reduction, Zinc-promoting coupling reaction

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