高等学校化学学报

高等学校化学学报 ›› 1996, Vol. 17 ›› Issue (2): 332.

• 研究简报 • 上一篇    

新型阴离子型温敏水凝胶

王昌华, 曹维孝   

  1. 北京大学化学与分子工程学院, 北京 100871
  • 收稿日期:1995-03-08 出版日期:1996-02-24 发布日期:1996-02-24
  • 通讯作者: 曹维孝
  • 作者简介:王昌华,男,26岁,硕士研究生.
  • 基金资助:

    国家自然科学基金

Novel Anionic Thermosensitive Hydrogels

WANG Chang-Hua, CAO Wei-Xiao   

  1. College of Chemistry and Molecular Engineering, Peking University, Beijing 1000871
  • Received:1995-03-08 Online:1996-02-24 Published:1996-02-24

PDF (PC)

被引次数

18

关键词: 温敏水凝胶, 溶胀比, N-异丙基丙烯酰胺

Abstract: Novel anionic thermosensitive hydrogels were prepared by the copolymerization of N-isopropyl acrylamide(NIPA) with 3-sulfopropyl acrylate potassium salt(SPAP) as anionic monomer in the presence of methylene-bisacrylamide(MBA).The hydrogels exhibit excellent thermosensitive behavior and high swelling properites,In the feed ratios varing from 1.0% to 2.0%(molar ratio) SPAPcontent the hydrogels possess the volume ratios of 27～38 and the sensitive temperatures varied from 35℃ to 38℃,which are very close to the human body temperature,and very important for Drug Delivery Systems(DDS).

Key words: Thermosensitive hydrogel, Swelling ratio, N-isopropyl acrylamide

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