选择脱卤还原反应的研究

高等学校化学学报 ›› 1990, Vol. 11 ›› Issue (8): 897.

选择脱卤还原反应的研究

关烨第, 胡颉, 熊波, 周德岭

北京大学化学系

收稿日期:1989-09-12 出版日期:1990-08-24 发布日期:1990-08-24
通讯作者: 关烨第

Studies on the Selective Dehalogenation Reduction Reaction

Guan Yedi, Hu Jie, Xiong Bo, Zhou Deling

Department of Chemistry, Peking University, Beijing

Received:1989-09-12 Online:1990-08-24 Published:1990-08-24

摘要/Abstract

摘要： Ramasamy、Osuka等用NaHTe/EtOH研究了二卤代物的脱邻二溴^[1]、偕二溴^[2]反应和α-溴代羰基化合物^[3]的脱卤还原反应,我们选择结构不同的卤代物以NaHTe还原,发现在水介质和催化量碲代替计算量碲时也能顺利地进行这类反应,其反应条件温和,产率高,是有机官能团转化的好方法。

关键词: 卤代物, 催化量碲, 脱卤还原

Abstract: Various halogen compounds were effectively reduced by sodium hydrogen telluride in aqueous solution or ethanol under mild conditions and in good yields, particularly when a molecule contains other groups such as carbonyl, carboxyl, ester and benzyl.The typical process occurred with a stbichiometric amount or a catalytic amount of tellurium. The mechanism may be envisaged that nucleophilic attack of hydrogen telluride ion (HTe^-) on the a-car-bon atoms could lead to the leaving of the halogen from a-carbon atoms.

Key words: Halogen compound, Catalytic amount of tellurium, Dehalogenation reduction

TrendMD:

关烨第, 胡颉, 熊波, 周德岭. 选择脱卤还原反应的研究. 高等学校化学学报, 1990, 11(8): 897.

Guan Yedi, Hu Jie, Xiong Bo, Zhou Deling . Studies on the Selective Dehalogenation Reduction Reaction. Chem. J. Chinese Universities, 1990, 11(8): 897.