高等学校化学学报 ›› 1990, Vol. 11 ›› Issue (4): 417.

• 研究论文 • 上一篇    下一篇

盐酸黄连素示波电位滴定法的研究

胡效亚, 冷宗周   

  1. 扬州师范学院化学系
  • 收稿日期:1988-09-27 出版日期:1990-04-24 发布日期:1990-04-24
  • 通讯作者: 胡效亚

Oscillo-Potentiometric Titration of Berberine Hydrochioride

Hu Xiaoya, Leng Zongzhou   

  1. Department of Chemistry, Yangzhou Tencher's College, Yangzhou
  • Received:1988-09-27 Online:1990-04-24 Published:1990-04-24

摘要: 黄连素(小檗碱)是一种重要的抗菌素药,用于治疗细菌性痢疾和一般炎症。现行的分析方法为碘量法[1],比较烦琐。本文将示波电位滴定法[2]中的金属片电极涂上一层含活性物质的PVC膜,使电极对黄连素等有机药物产生一定的响应,可用于四苯硼酸钠直接滴定黄连素的终点指示。该方法比药典法[1]、直接电位法[3]更简便、直观,易推广使用,同时也扩大了示波电位滴定法的应用范围。

关键词: 示波电位滴定, 四苯硼酸钠, 黄连素

Abstract: The copper plate coated with PVCmembrane (containning berberine-tetraphenylborate) was used as the indicator electrode, while berberine was titrated with sodium tetraphenylborate by oscillo-potentiometric titration. This method is precise, audio-visual, simple and convenient and can be used in the determination of other drugs.

Key words: Oscillo-potentiometric titration, Sodium tetraphenylborate, Berberine

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