黄酮类化合物研究(ⅩⅣ)—溴代异黄酮合成中的脱溴反应

高等学校化学学报 ›› 1990, Vol. 11 ›› Issue (1): 99.

黄酮类化合物研究(ⅩⅣ)—溴代异黄酮合成中的脱溴反应

岳保珍, 周则卫, 蔡孟深

北京医科大学药学院

收稿日期:1988-09-04 出版日期:1990-01-24 发布日期:1990-01-24
通讯作者: 蔡孟深

Studies on Flavonoids(XIV)— Debromination Reaction in the Synthesis of Bromoisoflavones

Yue Baozhen, Zhou Zewei, Cai Mengsben

College of Pharmacy, Beijing Medical University, Beijing

Received:1988-09-04 Online:1990-01-24 Published:1990-01-24

摘要/Abstract

摘要： 我们曾报道2-溴间苯二酚在BF₃催化下酰化时的脱溴现象^[1]。本文在以下述反应制备6-溴代异黄酮时发现4-溴间苯二酚脱溴现象更为显著。

关键词: 6-溴代异黄酮, 脱溴反应, 溴正离子

Abstract: 6- Bromoisoflavone was prepared from 4- bromoresorcinol. Debromination reaction was found in the acylation of the starting material by using BF₃ as catalyst, and a by-product, 4,6-dibro-moresorcinol, was also isolated. The reaction mechanism probably involves a bromonium ion.

Key words: 6-Bromoisoflavone, Debromination, Bromonium ion

TrendMD:

岳保珍, 周则卫, 蔡孟深. 黄酮类化合物研究(ⅩⅣ)—溴代异黄酮合成中的脱溴反应. 高等学校化学学报, 1990, 11(1): 99.

Yue Baozhen, Zhou Zewei, Cai Mengsben . Studies on Flavonoids(XIV)— Debromination Reaction in the Synthesis of Bromoisoflavones. Chem. J. Chinese Universities, 1990, 11(1): 99.