高等学校化学学报

高等学校化学学报 ›› 1989, Vol. 10 ›› Issue (4): 373.

• 研究论文 • 上一篇    下一篇

合成α-芳基-β-硝基乙基膦酸酯的新方法

李玉桂1, 王国洪1, 张殿坤1, 刘廷仰1, 缪方明2, 刘小兰2, 曹金鸿3, 郭杭州3   

  1. 1. 南开大学元素有机化学研究所;
    2. 天津师范大学化学系;
    3. 中国军事医学科学院
  • 收稿日期:1987-12-24 出版日期:1989-04-24 发布日期:1989-04-24
  • 通讯作者: 李玉桂
  • 基金资助:

    国家自然科学基金

A New Method to Synthesize a-Aryl-p-Nitroethylphosphonates

Li Yugui1, Wang Guohong1, Zhang Diankun1, Liu Tingyang1, Miao Fangming2, Liu Xiaolan2, Cao Jinhong3, Guo Hangzhou3   

  1. 1. Institute of Elemento-Organia Chemistry, Nankai University, Tianjin;
    2. Department of Chemistry, Tianjin Normal University, Tianjin;
    3. Academy of Military Medical Science, Beijing
  • Received:1987-12-24 Online:1989-04-24 Published:1989-04-24

PDF (PC)

摘要： 本文研究了酸性亚磷酸酯与α-芳基-β-硝基烯烃在三甲基氯硅烷和缚酸剂存在下的Arbuzov-Michael反应。不需制备硅烷化的亚磷酸酯,即可得到产率高的Ia-n,其结构由元素分析、IR、1HNMR和MS证实。这类分子中磷原子上的O,O-二烷基为磁不等价基团的结论亦为X-射线晶体结构分析所证实。

关键词: 亚磷酸酯, &alpha, -芳基-&beta, -硝基烯, 三甲基氯硅烷, &alpha, -芳基-&beta, -硝基乙基膦酸酯

Abstract: This paper reports a one-pot reaction of the Arbuzov-Michael addition of acidic phosphites to α-aryl-β-nitroalkenes. The reaction was carried out smoothly with an excess of trimethylchlorosilane and acid-binding agents, giving high yields of addition products Ia-n. The structures of these compounds were characterized by elemental analysis, IR, 1HNMR and MS. It was found that in these molecules the O,O-dialkyl groups on the phosphorus atom were unequivalent. This fact was also confirmed by the X-ray structure determination of one representative compound, Ij.

Key words: Phosphite, α-Aryl-β-nitroalkene, Trimethylchlorosilane, α-Aryl-β-nitroethylphosphonates

TrendMD: