Interaction of Copolymer-Zn with Polypeptide

Chem. J. Chinese Universities

• 研究快报 • Previous Articles

Interaction of Copolymer-Zn with Polypeptide

ZHAO Jian-Xin¹, QIAO Yi-Tao¹, FENG Jing¹, LUO Zhao-Feng², YUAN Zhi¹*

1. Key Laboratory of Functional Polymer Materials, Ministry of Education, Institute of Polymer Chemistry, Nankai University, Tianjin 300071, China;
2. School of Life Sciences, University of Science and Technology of China, Hefei 230027, China

Received:2007-10-08 Revised:1900-01-01 Online:2008-03-10 Published:2008-03-10
Contact: YUAN Zhi

Abstract

Abstract: A new copolymer(C) was designed and synthesized. Isothermal Titration Calorimetry(ITC) expe-riments showed the strong binding of C-Zn and the predetermined peptide sequences(DFLAE, appear in many peptides sequence which cumulate in serum of uremic patients). The further ITC experiments demonstrate that the binding is the result of the cooperative effect of coordination and hydrophobic interaction, which may provide further understanding on the mechanism of polymer-metal-peptide interaction and a structural basis for designing the adsorbents for the target peptide.

Key words: Polypeptide, Copolymer, Intermolecular interaction

CLC Number:

O632.19

TrendMD:

ZHAO Jian-Xin¹, QIAO Yi-Tao¹, FENG Jing¹, LUO Zhao-Feng², YUAN Zhi¹*. Interaction of Copolymer-Zn with Polypeptide[J]. Chem. J. Chinese Universities, doi: .

[1]	WANG Zhengwen, GAO Fengxiang, CAO Han, LIU Shunjie, WANG Xianhong, WANG Fosong. Synthesis and Property of CO₂ Copolymer⁃based UV-curable Polymer [J]. Chem. J. Chinese Universities, 2022, 43(7): 20220236.
[2]	LI Haibo, XIAO Changfa, JIANG Long, HUANG Yun, DAN Yi. Copolymerization of Methyl Acrylate and 1-Octene Catalyzed by the Loaded Aluminum Chloride on MCM-41 Molecular Sieve [J]. Chem. J. Chinese Universities, 2021, 42(9): 2974.
[3]	LIU Xiaojin, LI Ting, WANG Yang, DONG Weifu. Preparation of Terpolymer Microspheres with Broad Band UV-blocking Performance [J]. Chem. J. Chinese Universities, 2021, 42(6): 1965.
[4]	XU Mengyi, HUANG Xuewen, LI Xiaojie, WEI Wei, LIU Xiaoya. Fabrication of Biosensor Based on “Beads-on-a-String” Shaped Composite Nano-assembly Modified Screen Printed Electrode [J]. Chem. J. Chinese Universities, 2021, 42(6): 1768.
[5]	MA Zhuoyuan, WANG Dayang. Status and Prospect of Surface Wettability of Molecular Self-assembled Monolayers [J]. Chem. J. Chinese Universities, 2021, 42(4): 1031.
[6]	FAN Juanjuan, HAN Yuanyuan, CUI Jie. Monte Carlo Simulation of the Transformation Control of ABC Triblock Copolymer Micelles from Multicompartment Structure to Multicore Structure [J]. Chem. J. Chinese Universities, 2021, 42(3): 857.
[7]	XU Xiaozhou, LIU Yi, HE Minhui, MO Song, LAN Bangwei, ZHAI Lei, FAN Lin. Effect of Copolymerization Structure and Molecular Weight on Melt Fluidity and Thermal Properties of Thermoplastic Polyimide Resins [J]. Chem. J. Chinese Universities, 2021, 42(3): 919.
[8]	DU Xinyao, WANG Wei, LIN Yu, WU Guozhang. Synthesis and Optical Properties of Polycarbonates Copolymerized with Bisphenol Fluorene Moiety [J]. Chem. J. Chinese Universities, 2021, 42(12): 3765.
[9]	ZHANG Junying, PENG Wei, CHEN Ziwei, HE Aihua. Effect of the Polymerization Temperature on the Copolymerization of Butadiene and Isoprene Catalyzed by Supported Ziegler-Natta Catalyst [J]. Chem. J. Chinese Universities, 2020, 41(8): 1873.
[10]	GUO Qinrui, SHAO Huafeng, HE Aihua. Thermal-oxidative Aging Performance of TBIR Modified NR/BR Vulcanizates in Aircraft Tire Sidewall ^† [J]. Chem. J. Chinese Universities, 2020, 41(4): 789.
[11]	WU Yingfei,LI Hongyu,CAI Lei,HE Aihua. Structure and Properties of NBR/TBIR Composites with High Abrasion Resistance and Low Heat Built-up ^† [J]. Chem. J. Chinese Universities, 2020, 41(3): 565.
[12]	ZHANG Meng, WANG Shaosen, XIN Yuhao, LIU Xue, WU Qiuhua, ZHANG Guolin. Preparation and Drug Delivery Properties of Thermo/pH Dual Responsive Copolymer Composite Micelles of MPEG-b-PCL/PNVCL-b-PCL [J]. Chem. J. Chinese Universities, 2020, 41(12): 2822.
[13]	SHI Xiaoyu, WANG Songmeng, LIU Lingyan, CHANG Weixing, LI Jing. Controllable Synthesis of Amphiphilic Block Copolymer PMnEOS-b-PAA and co-Assembly Morphologies of PMDEOS-b-PAA/PS-b-PAA [J]. Chem. J. Chinese Universities, 2020, 41(11): 2545.
[14]	WANG Lin, ZHANG Yanhui, Arzugul Muslim, LAN Haidie. Morphology and Size Regulation of Polyaniline Induced by PS-b-P2VP as Template and Its Electrochemical Characters [J]. Chem. J. Chinese Universities, 2019, 40(8): 1748.
[15]	ZHANG Yuefa, SHAO Huafeng, WANG Riguo, HE Aihua. Structure and Properties of Sidewall Compounds for Aircraft Tyre Modified by TBIR [J]. Chem. J. Chinese Universities, 2019, 40(8): 1733.

Interaction of Copolymer-Zn with Polypeptide

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments