Synthesis, Properties and Antiviral Activity of Keggin Molybdogemnium Heteropoly Blues

Chem. J. Chinese Universities ›› 2000, Vol. 21 ›› Issue (12): 1791.

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Synthesis, Properties and Antiviral Activity of Keggin Molybdogemnium Heteropoly Blues

LIU Jie¹, ZHANG Qian-Ling¹, WANG Li-Jun-WANG En-Bo², HUANG Jin-Wang³, JI Liang-Nian¹

1. State Key Laboratoryof Ultrafast Laser Spectroscopy, Departmentof Chemistry, Zhongshan University, Guang zhou 510275, China;
2. Jilin Medical University, Jilin 132001, China;
3. Department of Chemistry, Northeast Normal University, Changchun 130024, China

Received:1999-10-11 Online:2000-12-24 Published:2000-12-24

Abstract

Abstract: Rare earth molybodogemanium 2e, 4e heteropoly blues, LnH₃[GeMo_{10_{^ⅥMo₂^ⅤO₄₀]·8H₂Oand LnH₅[GeMo_{8_{^ⅥMo_{4_{ⅤO₄₀]·8H₂O(Ln=La, Ce, Nd, Sm, Gd), have been prepared and characterized by IR, UV, TG DTA, XPS, ESR.It is found that the structures of the heteropoly blues still retain the Keggin structure with a slight difference compared with their un reduced compounds.The in vivo activity of Pr(2) against influenza virus(FM1) in the mice was investigated.Pr(2) was administrated perorally(po) and intraperitoneally(i.p) to 14-16 g Kunming mice infected with FM_1.The results show that in contrast to the positive ribavirin, the curative effect of Pr(2) proved to be better and i.padministration was more effective than poadministration}}}}}}

Key words: Rare earth elements, Heteropoly blues, Synthesis, Property, Antiviral activity

CLC Number:

O612.6

TrendMD:

LIU Jie, ZHANG Qian-Ling, WANG Li-Jun-WANG En-Bo, HUANG Jin-Wang, JI Liang-Nian. Synthesis, Properties and Antiviral Activity of Keggin Molybdogemnium Heteropoly Blues[J]. Chem. J. Chinese Universities, 2000, 21(12): 1791.

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Synthesis, Properties and Antiviral Activity of Keggin Molybdogemnium Heteropoly Blues

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