Chemical Journal of Chinese Universities ›› 1991, Vol. 12 ›› Issue (5): 672-676.

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Studies on Transfer Mechanism of Chloroquine at the Aqueous 1,2-Dichloroethane Interface

Xiao Jun, Lin Song, Nie Li-hua, Yao Shou-zhuo   

  1. Department of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082
  • Received:1989-11-21 Online:1991-05-24 Published:1991-05-24

Abstract: Transfer processes of chloroquine in aqueous phase, non-ionized chloroquine and chloro-quine existing as ion-pair complex with tetraphenylborate in organic phase across the aqueous 1,2-CH2C1CH2C1interface were studied by polarography with the electrode of drop electrolyte (EDE), cyclic voltammetry with current scanning and chronopotentiometry, respectively. Their transfer mechanisms were proposed. The effect of pH of aqueous phase, the concentration of chloroquine and the flow-rate of EDE as well as the scanning rate on transfer behavior was discussed. The interfacial potential difference and Gibbs transfer energy were calculated as ΔDCEWφ=0. 06 V, ΔGtruo,DCE→W=-11. 58 kJ/mol, respectively.

Key words: Chloroquine, Water/1,2-dichloroethane interface, Oil/water interface, Ion transfer