Chem. J. Chinese Universities ›› 2011, Vol. 32 ›› Issue (9): 2010.

• Review • Previous Articles     Next Articles

Recent Progresses in Sugar\|functionalized Macrocyclic Compounds

YANG Fen1,2, ZHANG Xin-Jian1, CHEN Qi1, YAN Chao-Guo2*, HAN Bao-Hang1*   

  1. 1.  National Center for Nanoscience and Technology, Beijing 100190, China;
    2.  College of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, China
  • Received:2011-03-29 Revised:2011-06-13 Online:2011-09-10 Published:2011-08-11
  • Contact: HAN Bao-Hang;YAN Chao-Guo E-mail:hanbh@nanoctr.cn;cgyan@yzu.edu.cn
  • Supported by:

    国家重大科学研究计划项目(批准号:  2011CB932500)和国家自然科学基金(批准号:  20972035, 21002017)资助.

Abstract: Carbohydrates, as a special substrate of specific receptors in many biological processes, play an important role in information communication. In recent years, more and more novel sugar-functionalized macrocyclic compounds such as calixarenes, cyclodextrins and crown ethers have been efficiently prepared and show the potential applications in lectin-pecific biological binding, selective ion recognition, and chiral catalysis. Introducing sugars into the macrocyclic system can not only produce various novel multivalent glycoconjugates, but also provide new binding sites for the macrocyclic compounds, which attracts more and more attention. In this review, recent progresses in the synthesis and applications of sugar-functionalized macrocyclic molecules have been summarized.

Key words: Carbohydrate; , Host-guest recognition; , Macrocyclic compound; , Supramolecule

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