Chem. J. Chinese Universities ›› 2011, Vol. 32 ›› Issue (6): 1318.

• Articles • Previous Articles     Next Articles

Three New Terpenoids from Salvia przewalskii Maxim.

YANG Yang1, WU Zhi-Jun1, YANG Ying-Bo1, LAI Wei1, SUN Lian-Na2, CHEN Wan-Sheng1*   

  1. 1. Department of Pharmacy, Changzheng Hospital, Second Military Medical University of PLA, Shanghai 200003, China;
    2. School of Pharmacy, Second Military Medical University of PLA, Shanghai 200433, China
  • Received:2010-07-07 Revised:2010-11-23 Online:2011-06-10 Published:2011-05-10
  • Contact: CHEN Wan-Sheng E-mail:chenwanshengsmmu@yahoo.com.cn
  • Supported by:

    上海科学技术委员会科技专项资金项目(批准号: 02DZ19107)资助.

Abstract: Salvia przewalskii Maxim. (Labiatae) is widely distributed in the western areas of China, such as Gansu, Sichuan, Yunnan and Tibet provinces. And it has been used as a substitute in Chinese folk medicine for S. miltiorrhiza Bge. (Dan Shen). The mainly chemical constituents of S. przewalskii are diterpenoids and phenolic acids. In our search, isolation and purification were carried out repeatedly by silica gel, Sephadex LH-20, ODS C18 and MCI gel column chromatography. Two new diterpenoids, named ganxintriol A (1) and ganxintriol B (2), and a new monoterpenoid glycoside, named ganxinoside A (3), were obtained from 50% ethanol extract of the roots and rhizomes of S. przewalskii. Their structures were established on the basis of physical methods, chemical methods and spectral data.

Key words: Salvia przewalskii Maxim., Chemical constituent, Ganxintriol A, Ganxintriol B, Ganxinoside A

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