Synthesis and Herbicidal Activities of 4-Alkoxy/benzyloxyphenyltetrazoles and 1,3,4-Oxadiazoles

Chem. J. Chinese Universities

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Synthesis and Herbicidal Activities of 4-Alkoxy/benzyloxyphenyltetrazoles and 1,3,4-Oxadiazoles

WANG Bao-Lei, LI Zheng-Ming*, LI Yong-Hong, WANG Su-Hua

Elemento-Organic Chemistry Institute, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China

Received:2007-04-16 Revised:1900-01-01 Online:2008-01-10 Published:2008-01-10
Contact: LI Zheng-Ming

Abstract

Abstract: Tetrazoles and 1,3,4-oxadiazoles are important heterocyclic compounds with a wide range of pharmaceutical and biological activity. Their syntheses and herbicidal activity have been of interest for a long time. In our previous research, a series of 4-alkoxy(benzyloxy)benzamidines were synthsized and showed a favourable herbicidal activity and KARI inhibitory activity. For searching potent herbicidal activity compounds, in this paper, five 4-alkoxy/benzyloxyphenyltetrazoles and seventeen new 2-substituted-5-(4-alkoxy/benzyloxy)phenyloxadiazoles were designed on the basis of the structure of 4-alkoxy(benzyloxy)benzamidine and synthesized via 4-cyanophenol as the starting material. All synthesized novel compounds were confirmed by elemental analysis, ¹H NMR and MS. The preliminary herbicidal assay indicates that some of them displayed a good herbicidal activity on di-cotyledonous rape(Brassica campestris) and mono-cotyledonous barnygrass(Echinochloa crusgalli).

Key words: Tetrazole, Oxadiazole, Herbicidal activity

CLC Number:

O621
O626

TrendMD:

WANG Bao-Lei, LI Zheng-Ming*, LI Yong-Hong, WANG Su-Hua. Synthesis and Herbicidal Activities of 4-Alkoxy/benzyloxyphenyltetrazoles and 1,3,4-Oxadiazoles[J]. Chem. J. Chinese Universities, doi: .

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Synthesis and Herbicidal Activities of 4-Alkoxy/benzyloxyphenyltetrazoles and 1,3,4-Oxadiazoles

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