Silver Biomimetic Mineralization in vitro with Inorganicbinding  Peptide AG4(NPSSLFRYLPSD) Immobilized on PET Film

Chem. J. Chinese Universities ›› 2006, Vol. 27 ›› Issue (1): 5.

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Silver Biomimetic Mineralization in vitro with Inorganicbinding Peptide AG4(NPSSLFRYLPSD) Immobilized on PET Film

ZHANG Xu¹, CHEN JinChun¹, YANG Peng², YANG WanTai²

1. College of Life Science and Technology, 2. College of Material Science and Engineering,
Beijing University of Chemical Technology, Beijing 100029, China)

Received:2005-01-18 Online:2006-01-10 Published:2006-01-10
Contact: CHEN JinChun,E-mail: jingchunchen@hotmail.com

Abstract

Abstract:

AbstractAG4(NPSSLFRYLPSD)is a peptide that specifically and selectively binds to silver resulting from Dr. Stony′s phage display peptide combination library. The peptides that have similar characteristic are defined as inorganicbinding peptides. In our experiment, AG4 was adsorbed on the surface of protonated PET-N(CH₃)₂film for studying its biomineralization behavior in vitro. Based on the XPS results of both silver crystallite on AG4/PET-N⁺(CH₃)₂ film and AgNO₃ salt, we approved that Ag⁺ exactly reduced to Ag⁰ and further formed silver crystallites. In addition, the images of SEM revealed that silver crystallite was 1-2 μm in size with a square shape and a triangular shape. At last, we discussed the reaction mechanism possibly occurring in this process.

Key words: Inorganicbinding peptides; PET film; Silver Micro-crystallite; Molecular biomimetics

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ZHANG Xu, CHEN Jin-Chun, YANG Peng, YANG Wan-Tai. Silver Biomimetic Mineralization in vitro with Inorganicbinding Peptide AG4(NPSSLFRYLPSD) Immobilized on PET Film[J]. Chem. J. Chinese Universities, 2006, 27(1): 5.

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Silver Biomimetic Mineralization in vitro with Inorganicbinding Peptide AG4(NPSSLFRYLPSD) Immobilized on PET Film

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