Abstract: Three water-soluble β-alanine C₆₀ adducts with different addition numbers, C₆₀(NHCH₂CH₂COONa) nH n(n=1,5,9), were synthesized. The products were characterized by FTIR, ¹HNMR and elemental analysis. The antioxidant activity of these C₆₀ adducts as the quencher for superoxide anion radical O₂^-· was evaluated by chemiluminescence in the system of pyrogallol-luminol. The results indicate that the three C₆₀ derivatives are all excellent quencher for superoxide anion radical O₂^-·. The concentrations of 50% inhibition are 252, 140, 112 μmol/L respectively. This high efficiency should be attributed to many factors such as the numbers of remaining double bonds, donor effect of amino group and steric effect. However, the above results also suggest the effect of the adducted β-alanine groups is predominated in this system.

Key words: β-Alanine C₆₀ derivatives, Superoxide anion radical O₂^-·, Auto-oxidation of pyrogallol, Chemiluminescence