Separation and Structure Determination of a New 19-nor-Spongian Diterpenoid

Chem. J. Chinese Universities ›› 2003, Vol. 24 ›› Issue (5): 817.

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Separation and Structure Determination of a New 19-nor-Spongian Diterpenoid

SU Jing-Yu¹, LIN Cui-Wu^1,3, ZENG Long-Mei¹, YAN Su-Jun¹, FENG Xiao-Long², CAI Ji-Wen¹

1. School of Chemistry and Chemical Engineering;
2. Instrumentation Analysis and Research Center, Zhongshan University, Guangzhou 510275;
3. Department of Chemistry, Guangxi University, Nanning 530004, China

Received:2002-04-12 Online:2003-05-24 Published:2003-05-24

Abstract

Abstract: A new 19-nor-spongian diterpene, zimoclactone A(1) together with a known compound, cholest-5,7-dien-3β-ol(2) were isolated from the Spongia zimocca aubspecles irregularia of marine sponge. The structure of compound 1 was determined by spectroscopic methods as well as X-ray diffraction analysis. Compound 1 showed a moderate cytotoxic activity against P388 cell lines.

Key words: Marine sponge, 19-nor-Spongian diterpenoid, Spongia zimocca, X-ray single crystal diffrac- tion analysis

CLC Number:

O629.6

TrendMD:

SU Jing-Yu, LIN Cui-Wu, ZENG Long-Mei, YAN Su-Jun, FENG Xiao-Long, CAI Ji-Wen. Separation and Structure Determination of a New 19-nor-Spongian Diterpenoid[J]. Chem. J. Chinese Universities, 2003, 24(5): 817.

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Separation and Structure Determination of a New 19-nor-Spongian Diterpenoid

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