Cyclization Reactions of 3,3-Dimethyl-1-(1H-1,2,4-triazolo-1-yl)-2- butanone or Substituted 1-(1H-1,2,4-Triazolo-1-yl)acetophenone with Dibromide Compounds and Its Biological Activities

Abstract

Abstract: The title compounds 3 and 4 were prepared by nucleophilic substitution reaction of compounds 1 with dibromide 2. Their structures were determined by elementary analysis, 1H NMR, IR, EI-MS and X-ray diffraction method. The reaction procedure was also studied in detail. From the screening results of biological activities, most compounds possess good fungicidal activities, especially against Puccinia recondita.

Key words: Triazole, Dibromide, Nucleophilic substitution reaction, Biological activities

CLC Number:

O626.26

TrendMD:

ZHANG Yao-Mou, CHEN Wen-Bin, JIN Gui-Yu . Cyclization Reactions of 3,3-Dimethyl-1-(1H-1,2,4-triazolo-1-yl)-2- butanone or Substituted 1-(1H-1,2,4-Triazolo-1-yl)acetophenone with Dibromide Compounds and Its Biological Activities[J]. Chem. J. Chinese Universities, 2003, 24(3): 431.

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Cyclization Reactions of 3,3-Dimethyl-1-(1H-1,2,4-triazolo-1-yl)-2- butanone or Substituted 1-(1H-1,2,4-Triazolo-1-yl)acetophenone with Dibromide Compounds and Its Biological Activities

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