Study on Properties of ssDNA-Carbonized Resin Rheumatoid Arthritis Immunoadsorbent

Chem. J. Chinese Universities ›› 2001, Vol. 22 ›› Issue (S1): 269.

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Study on Properties of ssDNA-Carbonized Resin Rheumatoid Arthritis Immunoadsorbent

YU Yao-Ting, WANG Lian-Yong, LU Jing, CHEN Chang-Zhi

Institute for Molecular Biology, Bioactive Material Research Laboratory, Nankai University, Tianjin 300071, China

Received:2001-08-07 Online:2001-12-31 Published:2001-12-31
Contact: yaoting@publicl.itp.tj.cn E-mail:yaoting@publicl.itp.tj.cn

Abstract

Abstract:

In this paper, The adsorption properties of ssDNA-carbonized resin rheumatoid arthritis immunoadsorbent were studied,Its specificity for adsorption of RF、hemocompatibility、stability and using safety were evaluated. The results show that the optimum saturation adsorption opacities of the adsorbent for IgMRF、IgGRF and IgARF were 2458、2877 and 11OOIU/mL when immobilized amount of ssDNA was 0.4mg/mL,and the ssDNA-carbonized resin is a safe and effective immunoadsorbent for RA therapy, its potential clinical use is promising in the future.

Key words: Rheumatoid arthritis, Immunoadsorbent, Adsorption properties, ssDNA, Carbonized resin

CLC Number:

O636
R318

TrendMD:

YU Yao-Ting, WANG Lian-Yong, LU Jing, CHEN Chang-Zhi. Study on Properties of ssDNA-Carbonized Resin Rheumatoid Arthritis Immunoadsorbent[J]. Chem. J. Chinese Universities, 2001, 22(S1): 269.

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Study on Properties of ssDNA-Carbonized Resin Rheumatoid Arthritis Immunoadsorbent

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