Chem. J. Chinese Universities ›› 2001, Vol. 22 ›› Issue (6): 949.

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A Rare Long Conjugated Diterpene Ketene from the Marine Sponge Ircinia selaginea(Lamark)

YAN Su-Jun, ZHANG Guang-Wen, SU Jing-Yu, ZENG Long-Mei   

  1. Department of Chemistry, Zhongshan University, Guangzhou 510275, China
  • Received:2000-12-15 Online:2001-06-24 Published:2001-06-24

Abstract: Anew diterpene, irciniketene, was isolated from the marine sponge Ircinia selaginea(Lamark) collected from the sea around Baihai, Guangxi Province. Its structure was determined by spectroscopic methods. In the structure, a ketene function is connected with a long conjugated system via an allene unit. Irciniketene shows a moderate inhibition toward MGCand HepG2 tumor cell lines.

Key words: Marine sponge, Ircinia selaginea, Diterpene, Ketene, Biological activity

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