Chem. J. Chinese Universities ›› 2000, Vol. 21 ›› Issue (9): 1408.

• Articles • Previous Articles     Next Articles

Asymmetric Synthesis of Optically Active1,1'-Bi-2-naphthol

SU Wu, WANG Heng-Shan, DA Chao-Shan, WANG Rui    

  1. School of Life Sciences, State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China
  • Received:1999-10-11 Online:2000-09-24 Published:2000-09-24

Abstract: Experimental results are reported for the CuCl2-mediated asymmetric oxidative coupling of 2-naphthols in the presence of [-]α-methylbenzylamine to optically active (S)-(-)-1,1'-bi-2-naphthol. Under anhydrous conditions and with a 3∶1 molarity ratio of α-methylbenzylamine to 2-naphthol, a fair enantioselection has been observed(up to 80.6% ee).

Key words: Asymmetric synthesis, 1,1'-Bi-2-naphthol, α-Methylbenzylamine

CLC Number: 

TrendMD: