Chem. J. Chinese Universities ›› 1999, Vol. 20 ›› Issue (S1): 507.
• Biological Analysis • Previous Articles Next Articles
FANG Yu-Zhi, HE Pin-Gang, FENG Min
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Abstract:
Adriamycin (ADM) is an anthracycline antibiotic with highly antineoplastic activity which has been in wide clinical use for treatment of various types of cancers. A variety of biochemical evidence suggests that adriamycin function primarily at the DNA level by blocking the processes of replication and transcription. A number of papers have reported that metal ion affects the drug's activity.
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FANG Yu-Zhi, HE Pin-Gang, FENG Min. Circular Dichroism Study on Interaction between Adriamycin and DNA as well as Effect of Metal Ions[J]. Chem. J. Chinese Universities, 1999, 20(S1): 507.
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http://www.cjcu.jlu.edu.cn/EN/Y1999/V20/IS1/507