Synthesis of Some New Chromones and Pyrimidinones Containing 2-Phenyl-1,2,3-triazole

Abstract

Abstract: The preparation of five new 2-heterocyclic substituted chromones and of ten new related pyrimidinones is reported. Condensation of 2-hydroxy acetophenones Ⅰ_a-Ⅰ_ewith 2-phenyl-1,2,3-triazole-4-carboxylic acid followed by Baker Venkataraman rearrangement led to 1,3-diketones Ⅲ_a-Ⅲ_e, which yielded chromones Ⅳ_a-Ⅳ_eon dehydration and pyrimidinones Ⅴ_a-Ⅴ_eon condensation with urea and thiourea respectively. Their structures were confirmed on the basis of elemental analysis, IR, ¹HNMR and MSs pectral data.

Key words: Triazole, Chromone, Pyrimidinones

CLC Number:

O626

TrendMD:

LIU Fang-Ming, YU Jian-Xin, WANG Mei, LIU Yu-Ting, CHEN Yao-Zu . Synthesis of Some New Chromones and Pyrimidinones Containing 2-Phenyl-1,2,3-triazole[J]. Chem. J. Chinese Universities, 1998, 19(7): 1082.

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Synthesis of Some New Chromones and Pyrimidinones Containing 2-Phenyl-1,2,3-triazole

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