Progress in Enzymatic Syntheses of Peptides and Peptide Derivatives in Organic Solvents

Abstract

Abstract: More attention has been focused on the enzymatic reaction in organic solvents in recent years. In this paper, syntheses of peptides and peptide derivatives containing unnatural constituent catalyzed by proteases and lipase were introduced. The influence of reaction conditions on the enzymatic synthesis and its application to the preparation of cyclopeptide and polypeptide were reviewed. The study of relationship between enzyme activity and its structure through modern spectroscopy was also discussed.

Key words: Protease, Enzymatic reaction, Peptides, Peptide derivatives, Organic solvent

CLC Number:

O629.72
Q55

TrendMD:

XING Guo-Wen, YE Yun-Hua, LI Chong-Xi . Progress in Enzymatic Syntheses of Peptides and Peptide Derivatives in Organic Solvents[J]. Chem. J. Chinese Universities, 1998, 19(10): 1602.

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Progress in Enzymatic Syntheses of Peptides and Peptide Derivatives in Organic Solvents

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