Chem. J. Chinese Universities ›› 1997, Vol. 18 ›› Issue (1): 132.

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Studies on the Utility of Chiral Reagent TMPEA for Measuring of Enantiomeric Purity of Chiral Ketones

Y0U Tian-Pa, HU Xiao-Ming, ZHANG Da-Yong   

  1. Department 0f Che, nistry, University of Science and Techn0logy of China, Hefei, 230O26
  • Received:1996-01-09 Online:1997-01-24 Published:1997-01-24

Abstract: Chiral amine TMPEAwas found to be useful in measuring of enantiomeric purityof chiraIketones.Four pairs of diastereomeric ketimines were prepared from R-(-)-TM-PEAand dl-TMPEAwith vari0us chiral ketones, the chemical shift differences between di-astereotopic protons (OCH3) were 0' 085-0.115, while fluorines (CF3) were 0' 17-0.45.

Key words: Chiral amine TMPEA, Measure, Chiral ketones, Enantiomeric purity

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