Chem. J. Chinese Universities ›› 1994, Vol. 15 ›› Issue (10): 1473.

• Articles • Previous Articles     Next Articles

Synthesis and Stereochemistry of 4-Substitutedphenyl -1,3,2-dioxaphosphorin Compounds(Ⅰ)─Reaction and Stereochemistry of Cyclic Phosphorochloridates and 3-Hydroxyisoxazole

SHAO Rui-Lian, YANG Min-Hua, ZHI Cheng-Xin   

  1. Institute of Elemento-Organic Chemistry, Nankai University, Tianjin, 300071
  • Received:1993-11-27 Revised:1994-03-04 Online:1994-10-24 Published:1994-10-24

Abstract: Owing to the biological activities of 3-hydroxyisoxazole and cyclic phosphate derivatives, some compounds possessing the two moieties were synthesized, the structural elucidation of these diastereomers was made depending on spectral analyses.The mechanism could be illustrated by the theories of trigonal bipyramide intermediate and pseudorotation.

Key words: dioxaphosphorin, Cis-trans isomers, Stereochemistry

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