CJCU

Chem. J. Chinese Universities ›› 1992, Vol. 13 ›› Issue (2): 181.

• Articles • Previous Articles     Next Articles

Studies on Determination of Trace Amitriptyline with Nafion-Modified Electrode

LENG Zong-zhou1, HU Xiao-ya1, JIN Li-tong2   

  1. 1. Department of Chemistry, Yangzhou Teachers' College, Yangzhou, 225002;
    2. Department of Chemistry, East China Normal University, Shanghai
  • Received:1991-01-03 Online:1992-02-24 Published:1992-02-24

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Abstract: Amitriptyline is an electroinactive cationic drugThis paper describes the method for the determination of trace amitriptyline with .Nafion-modified glassy crabon electrode, and discusses its reaction mechanismThe peak current of dopamine is decreased when amitriptyline is added to an electrolyte solution containing electroactive dopamineThere is a good linear relationship between the extent of the decrease in the peak current and the logarithmic concentration of amitriptyline in the range of 2.5×10-7～4.0×10-6 mol/LThe detection limit of the method is 1×10-7mol/LThe recovery is 95.3～106.0%, and the C.Vis 3.6%(n= 10).

Key words: Amitriptyline, Nafion-modified electrode, Cathodic stripping voitammetry

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