Chem. J. Chinese Universities ›› 1989, Vol. 10 ›› Issue (3): 311.

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The Effect of a New Electrolysis Mode on Asymmetric Reduction of Acetophenone

Li Ning, Chen Qirui, Pang Kaiqi   

  1. Shenyang College of Pharmacy
  • Received:1987-10-09 Online:1989-03-24 Published:1989-03-24

Abstract: This paper reports that acetophenone was reduced by asymmetric electrolysis with strychnine as a chiral inductor. The effect of the mode of electrolysis and the quantity of electricity on the reaction was investigated. It was found that the static-thin-layer mode was better than Kariv's method, the optical yield of a-carbinol was increased from 14.7% to 21.8%.

Key words: Acetophenone, Strychnine, Asymmetric electroysis

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