Studies on Synthetic Bilayer Membranes (Ⅱ)——Synthesis of HBBTAB and Self-Organizing Behavior of the Amphiphile in Dilute Aqueous Solution

Abstract

Abstract: Anovel single-chain amphiphile with the biphenyl moiety and the hexadecyl tail as the hy-drophobic group has been synthesized.The product was confirmed by elemental analysis,IRand ¹H NMR.The self-organizing behavior and aggregate vesicles in dilute aqueous solution of the amphiphile were examined by electron microscopy.This indicates that the titled amphiphile is of practical bilayer -forming, capable of organizing biomembrane used as a mimetic agent.The ¹H NMRspectra suggest that the molecular movement of the amphiphile was highly restricted within the aggregate.The gel-to-liquid crystal transition of the bilayer was shown by differential scanning calorimetry(DSC).These results show that the vesicle structures are composed of the bilayer similar to that of biomembranes.

Key words: Bilayer membranes, Vesicles, Amphiphile, 4-(4'-Hexadecyloxy-4-biphenyloxy) butyl trimethylammonium bromide

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Li Gouwen, Wang Zhiqiang, Tian Yongchi, Liang Yingqiu . Studies on Synthetic Bilayer Membranes (Ⅱ)——Synthesis of HBBTAB and Self-Organizing Behavior of the Amphiphile in Dilute Aqueous Solution[J]. Chem. J. Chinese Universities, 1989, 10(10): 1042.

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Studies on Synthetic Bilayer Membranes (Ⅱ)——Synthesis of HBBTAB and Self-Organizing Behavior of the Amphiphile in Dilute Aqueous Solution

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